Use “Rufus” to create Bootable Window 10 USB for Legacy BIOS and UEFI [ Ultimate Guide ]

With UEFI

To Create Bootable UEFI USB Flash Drive for Installing Windows 10 only with UEFI

Under Device, select the USB flash drive you want to format and use.
Under Boot selection, click/tap on the SELECT button, and navigate to and select your 64-bit Download Windows 10 ISO file.
Under Image option (if available), select Standard Windows installation.
Under the Partition scheme, select GPT.
Under the Target system, select UEFI (non-CSM).
Under Volume label, you can enter any name you like for the USB flash drive, or leave the default name.
Under File system, select FAT32 (if able). If the file is larger than 4GB, you will only be able to select NTFS.
Under Cluster size, select the (Default) (ex: 4096 bytes) it has listed.

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To Create Bootable USB Flash Drive for Installing Windows 10 only with Legacy BIOS (without UEFI).

A) Set Rufus using the settings below, click/tap on Start, and go to step 9 below. (see screenshot below).

Under Device, select the USB flash drive you want to format and use.
Under Boot selection, click/tap on the SELECT button, and navigate to and select your 32-bit or 64-bit Download Windows 10 ISO file.
Under the Image option (if available), select Standard Windows installation.
Under the Partition scheme, select MBR.
Under the Target scheme, select BIOS(or UEFI-CSM).
Under the Target system, select UEFI (non-CSM).
Under the Volume label, You can enter any name you like for the USB flash drive, or leave the default name.
Under the File system, select NTFS.
Under Cluster size, select the (Default) (ex: 4096 bytes) it has listed.